Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14

BACKGROUND: Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference (RNAi)-based targeted gene silencing is a quick,...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Ervin, Egle-Helene, Pook, Martin, Teino, Indrek, Kasuk, Valmar, Trei, Annika, Pooga, Margus, Maimets, Toivo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345057/
https://ncbi.nlm.nih.gov/pubmed/30678718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1144-x
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