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CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes

BACKGROUND: Systemic inflammation and the fever response to pathogens are coordinately regulated by IL-6 and IL-1β. We previously showed that CEACAM1 regulates the LPS driven expression of IL-1β in murine neutrophils through its ITIM receptor. RESULTS: We now show that the prompt secretion of IL-6 i...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Zhang, Zhifang, La Placa, Deirdre, Nguyen, Tung, Kujawski, Maciej, Le, Keith, Li, Lin, Shively, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345024/
https://ncbi.nlm.nih.gov/pubmed/30674283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-019-0287-y
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