Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element

Retrograde Bone Morphogenetic Protein (BMP) signaling in neurons is essential for the differentiation and synaptic function of many neuronal subtypes. BMP signaling regulates these processes via Smad transcription factor activity, yet the scope and nature of Smad-dependent gene regulation in neurons...

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Udgivet i:Nucleic Acids Res
Main Authors: Vuilleumier, Robin, Lian, Tianshun, Flibotte, Stephane, Khan, Zaynah N, Fuchs, Alisa, Pyrowolakis, George, Allan, Douglas W
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344883/
https://ncbi.nlm.nih.gov/pubmed/30476189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1135
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