Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element

Retrograde Bone Morphogenetic Protein (BMP) signaling in neurons is essential for the differentiation and synaptic function of many neuronal subtypes. BMP signaling regulates these processes via Smad transcription factor activity, yet the scope and nature of Smad-dependent gene regulation in neurons...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Vuilleumier, Robin, Lian, Tianshun, Flibotte, Stephane, Khan, Zaynah N, Fuchs, Alisa, Pyrowolakis, George, Allan, Douglas W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
Gene regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344883/
https://ncbi.nlm.nih.gov/pubmed/30476189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1135
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