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A VEGF-A/SOX2/SRSF2 network controls VEGFR1 pre-mRNA alternative splicing in lung carcinoma cells

The splice variant sVEGFR1-i13 is a truncated version of the cell membrane-spanning VEGFR1 receptor that is devoid of its transmembrane and tyrosine kinase domains. We recently showed the contribution of sVEGFR1-i13 to the progression and the response of squamous lung carcinoma to anti-angiogenic th...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Abou Faycal, Cherine, Gazzeri, Sylvie, Eymin, Beatrice
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344584/
https://ncbi.nlm.nih.gov/pubmed/30674935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36728-y
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