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Splice Variants of the RTK Family: Their Role in Tumour Progression and Response to Targeted Therapy
Receptor tyrosine kinases (RTKs) belong to a family of transmembrane receptors that display tyrosine kinase activity and trigger the activation of downstream signalling pathways mainly involved in cell proliferation and survival. RTK amplification or somatic mutations leading to their constitutive a...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343918/ https://ncbi.nlm.nih.gov/pubmed/28208660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020383 |
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