Discovery of a New Natural Product and a Deactivation of a Quorum Sensing System by Culturing a “Producer” Bacterium With a Heat-Killed “Inducer” Culture

Herein we describe a modified bacterial culture methodology as a tool to discover new natural products via supplementing actinomycete fermentation media with autoclaved cultures of “inducer” microbes. Using seven actinomycetes and four inducer microbes, we detected 28 metabolites that were induced i...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Liang, Libang, Sproule, Amanda, Haltli, Brad, Marchbank, Douglas H., Berrué, Fabrice, Overy, David P., McQuillan, Kate, Lanteigne, Martin, Duncan, Noelle, Correa, Hebelin, Kerr, Russell G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344404/
https://ncbi.nlm.nih.gov/pubmed/30705672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03351
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