Discovery of a New Natural Product and a Deactivation of a Quorum Sensing System by Culturing a “Producer” Bacterium With a Heat-Killed “Inducer” Culture

Herein we describe a modified bacterial culture methodology as a tool to discover new natural products via supplementing actinomycete fermentation media with autoclaved cultures of “inducer” microbes. Using seven actinomycetes and four inducer microbes, we detected 28 metabolites that were induced i...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Liang, Libang, Sproule, Amanda, Haltli, Brad, Marchbank, Douglas H., Berrué, Fabrice, Overy, David P., McQuillan, Kate, Lanteigne, Martin, Duncan, Noelle, Correa, Hebelin, Kerr, Russell G.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344404/
https://ncbi.nlm.nih.gov/pubmed/30705672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03351
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