Discovery of a New Natural Product and a Deactivation of a Quorum Sensing System by Culturing a “Producer” Bacterium With a Heat-Killed “Inducer” Culture

Herein we describe a modified bacterial culture methodology as a tool to discover new natural products via supplementing actinomycete fermentation media with autoclaved cultures of “inducer” microbes. Using seven actinomycetes and four inducer microbes, we detected 28 metabolites that were induced i...

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Publicat a:Front Microbiol
Autors principals: Liang, Libang, Sproule, Amanda, Haltli, Brad, Marchbank, Douglas H., Berrué, Fabrice, Overy, David P., McQuillan, Kate, Lanteigne, Martin, Duncan, Noelle, Correa, Hebelin, Kerr, Russell G.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344404/
https://ncbi.nlm.nih.gov/pubmed/30705672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03351
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