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Mito-Tempo Protects against Acute Liver Injury but Induces Limited Secondary Apoptosis during the Late Phase of Acetaminophen Hepatotoxicity
We previously reported that delayed treatment with Mito-tempo (MT), a mitochondrial targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. However, whether this protection is sustained to the late phase of...
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| Publicat a: | Arch Toxicol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344320/ https://ncbi.nlm.nih.gov/pubmed/30324313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2331-8 |
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