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Design Criteria For Minimalist Mimics Of Protein-protein Interface Segments
Small molecules that can interrupt or inhibit protein-protein interactions (PPIs) are valuable as probes in chemical biology and medicinal chemistry, but they are also notoriously difficult to develop. Design of non-peptidic small molecules that mimic amino acid side-chain interactions in PPIs (“min...
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| Udgivet i: | Org Biomol Chem |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344279/ https://ncbi.nlm.nih.gov/pubmed/30629068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob02901f |
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