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Correlations between secondary structure- and protein-protein interface-mimicry: The Interface Mimicry Hypothesis

An active segment of the research community designing small molecules (“minimalist mimics” of peptide fragments) to interfere with protein-protein interactions have based their studies on an implicit hypothesis. Here we refer to this as the Secondary Structure Hypothesis, that might be defined as, “...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Taechalertpaisarn, Jaru, Lyu, Rui-Liang, Arancillo, Maritess, Lin, Chen-Ming, Perez, Lisa M., Ioerger, Thomas R., Burgess, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863600/
https://ncbi.nlm.nih.gov/pubmed/30847453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00204a
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