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Deamidation and isomerization liability analysis of 131 clinical-stage antibodies
Contemporary in vivo and in vitro discovery platform technologies greatly increase the odds of identifying high-affinity monoclonal antibodies (mAbs) towards essentially any desired biologically relevant epitope. Lagging discovery throughput is the ability to select for highly developable mAbs with...
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| Publicado no: | MAbs |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6343770/ https://ncbi.nlm.nih.gov/pubmed/30526254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1548233 |
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