JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer

BACKGROUND: Human microsatellite-stable (MSS) colorectal cancers (CRCs) are immunologically “cold” tumour subtypes characterized by reduced immune cytotoxicity. The molecular linkages between immune-resistance and human MSS CRC is not clear. METHODS: We used transcriptome profiling, in silico analys...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Giordano, Guido, Parcesepe, Pietro, D’Andrea, Mario Rosario, Coppola, Luigi, Di Raimo, Tania, Remo, Andrea, Manfrin, Erminia, Fiorini, Claudia, Scarpa, Aldo, Amoreo, Carla Azzurra, Conciatori, Fabiana, Milella, Michele, Caruso, Francesca Pia, Cerulo, Luigi, Porras, Almudena, Pancione, Massimo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343337/
https://ncbi.nlm.nih.gov/pubmed/30670049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-1019-5
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