JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer

BACKGROUND: Human microsatellite-stable (MSS) colorectal cancers (CRCs) are immunologically “cold” tumour subtypes characterized by reduced immune cytotoxicity. The molecular linkages between immune-resistance and human MSS CRC is not clear. METHODS: We used transcriptome profiling, in silico analys...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Giordano, Guido, Parcesepe, Pietro, D’Andrea, Mario Rosario, Coppola, Luigi, Di Raimo, Tania, Remo, Andrea, Manfrin, Erminia, Fiorini, Claudia, Scarpa, Aldo, Amoreo, Carla Azzurra, Conciatori, Fabiana, Milella, Michele, Caruso, Francesca Pia, Cerulo, Luigi, Porras, Almudena, Pancione, Massimo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343337/
https://ncbi.nlm.nih.gov/pubmed/30670049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-1019-5
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