Acetaldehyde Induces Neurotoxicity In Vitro via Oxidative Stress- and Ca(2+) Imbalance-Mediated Endoplasmic Reticulum Stress

Excessive drinking can damage brain tissue and cause cognitive dysfunction. Studies have found that the early stage of neurodegenerative disease is closely related to heavy drinking. Acetaldehyde (ADE) is the main toxic metabolite of alcohol. However, the exact mechanisms of ADE-induced neurotoxicit...

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Detalles Bibliográficos
Publicado en:Oxid Med Cell Longev
Main Authors: Cui, Jiahui, Liu, Yang, Chang, Xing, Gou, Wenfeng, Zhou, Xuejiao, Liu, Zi, Li, Zengqiang, Wu, Yingliang, Zuo, Daiying
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343137/
https://ncbi.nlm.nih.gov/pubmed/30728884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2593742
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