Acetaldehyde Induces Neurotoxicity In Vitro via Oxidative Stress- and Ca(2+) Imbalance-Mediated Endoplasmic Reticulum Stress

Excessive drinking can damage brain tissue and cause cognitive dysfunction. Studies have found that the early stage of neurodegenerative disease is closely related to heavy drinking. Acetaldehyde (ADE) is the main toxic metabolite of alcohol. However, the exact mechanisms of ADE-induced neurotoxicit...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Cui, Jiahui, Liu, Yang, Chang, Xing, Gou, Wenfeng, Zhou, Xuejiao, Liu, Zi, Li, Zengqiang, Wu, Yingliang, Zuo, Daiying
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343137/
https://ncbi.nlm.nih.gov/pubmed/30728884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2593742
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