Alcohol amplifies ketamine-induced apoptosis in primary cultured cortical neurons and PC12 cells through down-regulating CREB-related signaling pathways

Recreational use of ketamine (KET) has been increasing worldwide. Previous studies have demonstrated that KET induced neurotoxicity; however, few studies have examined how alcohol (ALC) affects KET-induced neurotoxicity. In light of the fact that some KET abusers combine KET with ALC, the present st...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zuo, Daiying, Sun, Feng, Cui, Jiahui, Liu, Yumiao, Liu, Zi, Zhou, Xuejiao, Li, Zengqiang, Wu, Yingliang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585325/
https://ncbi.nlm.nih.gov/pubmed/28874724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10868-z
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