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Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice

Glutamatergic synapses constitute a major excitatory neurotransmission system and are regulated by glutamate/glutamine (Gln) cycling between neurons and astrocytes. Gln synthetase (GS) produced by astrocytes plays an important role in maintaining the cycle. However, the significance of GS during syn...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Son, Hyeonwi, Kim, Sujeong, Jung, Doo-hyuk, Baek, Ji Hyeong, Lee, Dong Hoon, Roh, Gu Seob, Kang, Sang Soo, Cho, Gyeong Jae, Choi, Wan Sung, Lee, Dong Kun, Kim, Hyun Joon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342969/
https://ncbi.nlm.nih.gov/pubmed/30670758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36619-2
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