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Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice
Glutamatergic synapses constitute a major excitatory neurotransmission system and are regulated by glutamate/glutamine (Gln) cycling between neurons and astrocytes. Gln synthetase (GS) produced by astrocytes plays an important role in maintaining the cycle. However, the significance of GS during syn...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6342969/ https://ncbi.nlm.nih.gov/pubmed/30670758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36619-2 |
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