Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice

Glutamatergic synapses constitute a major excitatory neurotransmission system and are regulated by glutamate/glutamine (Gln) cycling between neurons and astrocytes. Gln synthetase (GS) produced by astrocytes plays an important role in maintaining the cycle. However, the significance of GS during syn...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Son, Hyeonwi, Kim, Sujeong, Jung, Doo-hyuk, Baek, Ji Hyeong, Lee, Dong Hoon, Roh, Gu Seob, Kang, Sang Soo, Cho, Gyeong Jae, Choi, Wan Sung, Lee, Dong Kun, Kim, Hyun Joon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342969/
https://ncbi.nlm.nih.gov/pubmed/30670758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36619-2
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