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Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes

Lymph node metastasis is of major prognostic significance for breast cancer. Lymph node metastasis arises at a very early stage in some patients. Using the data downloaded from the TCGA database, we studied the differences between primary tumors with and without lymph node metastasis at the multi-om...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Zhigang, Liu, Wei, Chen, Chong, Yang, Xiaolin, Luo, Yunping, Zhang, Bailin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342949/
https://ncbi.nlm.nih.gov/pubmed/30670769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36319-x
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