Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes

Lymph node metastasis is of major prognostic significance for breast cancer. Lymph node metastasis arises at a very early stage in some patients. Using the data downloaded from the TCGA database, we studied the differences between primary tumors with and without lymph node metastasis at the multi-om...

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Vydáno v:Sci Rep
Hlavní autoři: Wang, Zhigang, Liu, Wei, Chen, Chong, Yang, Xiaolin, Luo, Yunping, Zhang, Bailin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342949/
https://ncbi.nlm.nih.gov/pubmed/30670769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36319-x
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