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Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes

Lymph node metastasis is of major prognostic significance for breast cancer. Lymph node metastasis arises at a very early stage in some patients. Using the data downloaded from the TCGA database, we studied the differences between primary tumors with and without lymph node metastasis at the multi-om...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Wang, Zhigang, Liu, Wei, Chen, Chong, Yang, Xiaolin, Luo, Yunping, Zhang, Bailin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342949/
https://ncbi.nlm.nih.gov/pubmed/30670769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36319-x
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