Maintenance of the bladder cancer precursor urothelial hyperplasia requires FOXA1 and persistent expression of oncogenic HRAS

Tumorigenesis requires accumulation of genetic and epigenetic alterations, some of which drive tumor initiation. “Oncogene addiction” describes the phenomenon that (1) well-established cancers are dependent on one mutated oncogene or pathway for the maintenance of a malignant phenotype and that (2)...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Yee, Christopher H., Zheng, Zongyu, Shuman, Lauren, Yamashita, Hironobu, Warrick, Joshua I., Wu, Xue-Ru, Raman, Jay D., DeGraff, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342925/
https://ncbi.nlm.nih.gov/pubmed/30670749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36720-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky