Relative Bioavailability of Orally Dispersible Tablet Formulations of Levo‐ and Racemic Praziquantel: Two Phase I Studies

Orally dispersible tablet (ODT) formulations of levo praziquantel (L‐PZQ) and racemic PZQ (rac‐PZQ) are being developed to treat schistosomiasis in preschool‐aged children. Two crossover studies (N = 32 and 36, respectively) assessed the relative bioavailability of these ODTs vs. Cysticide in adults...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Bagchus, Wilhelmina Maria, Bezuidenhout, Deon, Harrison‐Moench, Eleanor, Kourany‐Lefoll, Elly, Wolna, Peter, Yalkinoglu, Oezkan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342245/
https://ncbi.nlm.nih.gov/pubmed/30536632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12601
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