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Comparative Bioavailability of Sulindac in Capsule and Tablet Formulations

The cyclooxygenase-2 (COX-2) enzyme appears to be an important target for cancer chemoprevention. Given the recent emergence of potentially serious cardiovascular toxicity associated with selective COX-2 inhibitors, nonsteroidal antiinflammatory drugs (NSAIDs), which inhibit both COX-1 and COX-2, ha...

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Autors principals: Reid, Joel M., Mandrekar, Sumithra J., Carlson, Elsa C., Harmsen, W. Scott, Green, Erin M., McGovern, Renee M., Szabo, Eva, Ames, Matthew M., Boring, Daniel, Limburg, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435402/
https://ncbi.nlm.nih.gov/pubmed/18349286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-07-2510
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