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Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma

Research on mevalonate kinase deficiency has revealed that it may lead to the development of renal angiomyolipomas (RAMLs). Thus, it was suspected that geranylgeranyl pyrophosphate synthase (GGPPS), a key enzyme in the mevalonate pathway, may be involved in the development of RAMLs. In the present s...

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Bibliografski detalji
Izdano u:Oncol Lett
Glavni autori: Zhao, Dan-Dan, Yuan, Jun, Cheng, Qi, Qi, Ya-Ling, Lu, Ke, Lai, Shan-Shan, Sun, Qian, Zhao, Yue, Fang, Lei, Jin, Mei-Ling, Yu, De-Cai, Qiu, Yu-Dong, Li, Chao-Jun, Chen, Jun, Xue, Bin
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341897/
https://ncbi.nlm.nih.gov/pubmed/30675208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9808
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