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Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma

Research on mevalonate kinase deficiency has revealed that it may lead to the development of renal angiomyolipomas (RAMLs). Thus, it was suspected that geranylgeranyl pyrophosphate synthase (GGPPS), a key enzyme in the mevalonate pathway, may be involved in the development of RAMLs. In the present s...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Zhao, Dan-Dan, Yuan, Jun, Cheng, Qi, Qi, Ya-Ling, Lu, Ke, Lai, Shan-Shan, Sun, Qian, Zhao, Yue, Fang, Lei, Jin, Mei-Ling, Yu, De-Cai, Qiu, Yu-Dong, Li, Chao-Jun, Chen, Jun, Xue, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341897/
https://ncbi.nlm.nih.gov/pubmed/30675208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9808
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