Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma

Research on mevalonate kinase deficiency has revealed that it may lead to the development of renal angiomyolipomas (RAMLs). Thus, it was suspected that geranylgeranyl pyrophosphate synthase (GGPPS), a key enzyme in the mevalonate pathway, may be involved in the development of RAMLs. In the present s...

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Vydáno v:Oncol Lett
Hlavní autoři: Zhao, Dan-Dan, Yuan, Jun, Cheng, Qi, Qi, Ya-Ling, Lu, Ke, Lai, Shan-Shan, Sun, Qian, Zhao, Yue, Fang, Lei, Jin, Mei-Ling, Yu, De-Cai, Qiu, Yu-Dong, Li, Chao-Jun, Chen, Jun, Xue, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341897/
https://ncbi.nlm.nih.gov/pubmed/30675208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9808
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