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CRISPR/Cas9-mediated cervical cancer treatment targeting human papillomavirus E6

High-risk human papillomavirus (HPV) is a common cause of cervical cancer. HPV E6 oncoprotein promotes the degradation of host tumor suppressor gene p53, leading to the development of tumors. Therapeutic strategies that specifically target E6, which is constitutively expressed in tumors and is not p...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Yoshiba, Takahiro, Saga, Yasushi, Urabe, Masashi, Uchibori, Ryosuke, Matsubara, Shigeki, Fujiwara, Hiroyuki, Mizukami, Hiroaki
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341785/
https://ncbi.nlm.nih.gov/pubmed/30675284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9815
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