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CRISPR/Cas9-mediated cervical cancer treatment targeting human papillomavirus E6

High-risk human papillomavirus (HPV) is a common cause of cervical cancer. HPV E6 oncoprotein promotes the degradation of host tumor suppressor gene p53, leading to the development of tumors. Therapeutic strategies that specifically target E6, which is constitutively expressed in tumors and is not p...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Yoshiba, Takahiro, Saga, Yasushi, Urabe, Masashi, Uchibori, Ryosuke, Matsubara, Shigeki, Fujiwara, Hiroyuki, Mizukami, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341785/
https://ncbi.nlm.nih.gov/pubmed/30675284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9815
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