Knockout of vasohibin‐2 reduces tubulin carboxypeptidase activity and increases paclitaxel sensitivity in ovarian cancer

Vasohibin‐1 (VASH1) is a VEGF‐inducible endothelium‐derived angiogenesis inhibitor, and vasohibin‐2 (VASH2), its homolog, exhibits proangiogenic activity. VASH2 is expressed by various cancer cells and accelerates tumor angiogenesis and progression. VASH2 was recently shown to exhibit tubulin carbox...

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Bibliographic Details
Published in:Cancer Med
Main Authors: Koyanagi, Takahiro, Saga, Yasushi, Takahashi, Yoshifumi, Tamura, Kohei, Yoshiba, Takahiro, Takahashi, Suzuyo, Taneichi, Akiyo, Takei, Yuji, Urabe, Masashi, Mizukami, Hiroaki, Fujiwara, Hiroyuki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
Subjects:
Clinical Cancer Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026928/
https://ncbi.nlm.nih.gov/pubmed/33710778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3841
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