Knockout of vasohibin‐2 reduces tubulin carboxypeptidase activity and increases paclitaxel sensitivity in ovarian cancer

Vasohibin‐1 (VASH1) is a VEGF‐inducible endothelium‐derived angiogenesis inhibitor, and vasohibin‐2 (VASH2), its homolog, exhibits proangiogenic activity. VASH2 is expressed by various cancer cells and accelerates tumor angiogenesis and progression. VASH2 was recently shown to exhibit tubulin carbox...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Koyanagi, Takahiro, Saga, Yasushi, Takahashi, Yoshifumi, Tamura, Kohei, Yoshiba, Takahiro, Takahashi, Suzuyo, Taneichi, Akiyo, Takei, Yuji, Urabe, Masashi, Mizukami, Hiroaki, Fujiwara, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026928/
https://ncbi.nlm.nih.gov/pubmed/33710778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3841
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