A gene expression assay for simultaneous measurement of microsatellite instability and anti-tumor immune activity

BACKGROUND: Clinical benefit from checkpoint inhibitors has been associated in a tumor-agnostic manner with two main tumor traits. The first is tumor antigenicity, which is typically measured by tumor mutation burden, microsatellite instability (MSI), or Mismatch Repair Deficiency using gene sequenc...

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Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Danaher, Patrick, Warren, Sarah, Ong, SuFey, Elliott, Nathan, Cesano, Alessandra, Ferree, Sean
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341623/
https://ncbi.nlm.nih.gov/pubmed/30665466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0472-1
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