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A gene expression assay for simultaneous measurement of microsatellite instability and anti-tumor immune activity
BACKGROUND: Clinical benefit from checkpoint inhibitors has been associated in a tumor-agnostic manner with two main tumor traits. The first is tumor antigenicity, which is typically measured by tumor mutation burden, microsatellite instability (MSI), or Mismatch Repair Deficiency using gene sequenc...
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| Publicado no: | J Immunother Cancer |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6341623/ https://ncbi.nlm.nih.gov/pubmed/30665466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0472-1 |
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