Defective negative regulation of Toll-like receptor signaling leads to excessive TNF-α in myeloproliferative neoplasm

Patients with myeloproliferative neoplasms (MPN) have high levels of inflammatory cytokines, some of which drive many of the debilitating constitutional symptoms associated with the disease and may also promote expansion of the neoplastic clone. We report here that monocytes from patients with MPN h...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Lai, Hew Yeng, Brooks, Stefan A., Craver, Brianna M., Morse, Sarah J., Nguyen, Thanh Kim, Haghighi, Nahideh, Garbati, Michael R., Fleischman, Angela G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2019
Gaiak:
Myeloid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341195/
https://ncbi.nlm.nih.gov/pubmed/30647074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018026450
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