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Females are less sensitive than males to the motivational- and dopamine-suppressing effects of kappa opioid receptor activation
The neuropeptide dynorphin (DYN) activates kappa opioid receptors (KORs) in the brain to produce depressive-like states and decrease motivation. KOR-mediated suppression of dopamine release in the nucleus accumbens (NAc) is considered one underlying mechanism. We previously showed that, regardless o...
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| Publicado en: | Neuropharmacology |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6339824/ https://ncbi.nlm.nih.gov/pubmed/30528327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.12.002 |
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