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Herpes simplex virus 1 ICP8 mutant lacking annealing activity is deficient for viral DNA replication
Most DNA viruses that use recombination-dependent mechanisms to replicate their DNA encode a single-strand annealing protein (SSAP). The herpes simplex virus (HSV) single-strand DNA binding protein (SSB), ICP8, is the central player in all stages of DNA replication. ICP8 is a classical replicative S...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338833/ https://ncbi.nlm.nih.gov/pubmed/30598436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817642116 |
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