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A herpes simplex virus type 1 mutant lacking the ICP0 introns reactivates with normal efficiency.

Previous evidence suggests that the latency-associated transcript (LAT) gene of herpes simplex virus type 1 appears to have a role during reactivation of latent virus because viruses which are null mutants in this gene reactivate slowly or less efficiently than wild-type viruses. Mapping studies hav...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Natarajan, R, Deshmane, S, Valyi-Nagy, T, Everett, R, Fraser, N W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249065/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5569-5573.1991
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