LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation

Though miR-205 function has been largely characterized, the nature of its host gene, MIR205HG, is still completely unknown. Here, we show that only lowly expressed alternatively spliced MIR205HG transcripts act as de facto pri-miRNAs, through a process that involves Drosha to prevent unfavorable spl...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Profumo, Valentina, Forte, Barbara, Percio, Stefano, Rotundo, Federica, Doldi, Valentina, Ferrari, Elena, Fenderico, Nicola, Dugo, Matteo, Romagnoli, Dario, Benelli, Matteo, Valdagni, Riccardo, Dolfini, Diletta, Zaffaroni, Nadia, Gandellini, Paolo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338800/
https://ncbi.nlm.nih.gov/pubmed/30659180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08153-2
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