miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition

BACKGROUND: Radiotherapy is one of the main treatment options for non-metastatic prostate cancer (PCa). Although treatment technical optimization has greatly improved local tumor control, a considerable fraction of patients still experience relapse due to the development of resistance. Radioresistan...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Autores principales: El Bezawy, Rihan, Tinelli, Stella, Tortoreto, Monica, Doldi, Valentina, Zuco, Valentina, Folini, Marco, Stucchi, Claudio, Rancati, Tiziana, Valdagni, Riccardo, Gandellini, Paolo, Zaffaroni, Nadia
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360656/
https://ncbi.nlm.nih.gov/pubmed/30717752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1060-z
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