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Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models

Preterm birth (PTB), the leading cause of neonatal morbidity and mortality, urgently requires novel therapeutic agents. Spontaneous PTB, resulting from preterm labor, is commonly caused by intrauterine infection/inflammation. Statins are well-established, cholesterol-lowering drugs that can reduce i...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Boyle, Ashley K., Rinaldi, Sara F., Rossi, Adriano G., Saunders, Philippa T. K., Norman, Jane E.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338657/
https://ncbi.nlm.nih.gov/pubmed/30312114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801104R
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