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Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models

Preterm birth (PTB), the leading cause of neonatal morbidity and mortality, urgently requires novel therapeutic agents. Spontaneous PTB, resulting from preterm labor, is commonly caused by intrauterine infection/inflammation. Statins are well-established, cholesterol-lowering drugs that can reduce i...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Boyle, Ashley K., Rinaldi, Sara F., Rossi, Adriano G., Saunders, Philippa T. K., Norman, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338657/
https://ncbi.nlm.nih.gov/pubmed/30312114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801104R
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