37.4 IMMUNOMODULATORY STRATEGIES FOR SCHIZOPHRENIA: PRECLINICAL EVIDENCES FOR DRUG REPURPOSING

BACKGROUND: Schizophrenia is associated with immune-inflammatory and oxidative stress mechanisms leading to activation of the tryptophan catabolite (TRYCAT) pathway, which ultimately together with dysfunctional N-methyl-D-aspartate receptors (NMDAR) may cause neuroprogression and all symptom cluster...

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Bibliografiske detaljer
Udgivet i:Schizophr Bull
Main Authors: Macedo, Danielle, Araujo, Tatiane, Filho, Adriano Chaves, de Lucena, David, Monte, Aline, Lima, Ricardo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Plenary/Symposia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455210/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz022.152
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