Lack of Benefit on Brain Edema, Blood–Brain Barrier Permeability, or Cognitive Outcome in Global Inducible High Mobility Group Box 1 Knockout Mice Despite Tissue Sparing after Experimental Traumatic Brain Injury

High mobility group box 1 (HMGB1) is a prototypical danger-associated molecular pattern molecule that is considered a late mediator of neuro-inflammation after traumatic brain injury (TBI). Prior studies have suggested that targeting HMGB1 may lead to neuroprotective effects, but none of these studi...

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Vydáno v:J Neurotrauma
Hlavní autoři: Aneja, Rajesh K., Alcamo, Alicia M., Cummings, Jessica, Vagni, Vincent, Feldman, Keri, Wang, Qingde, Dixon, C. Edward, Billiar, Timothy R., Kochanek, Patrick M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338570/
https://ncbi.nlm.nih.gov/pubmed/30045665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2018.5664
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