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Targeted Delivery of Antigen to Activated CD169(+) Macrophages Induces Bias for Expansion of CD8(+) T cells
Macrophages (MØs) expressing the endocytic sialic acid-binding immunoglobulin-like lectin 1 (siglec-1, CD169, sialoadhesin) are known to be adept at antigen capture — primarily due to their strategic location within lymphatic tissues. Antigen concentrated in these cells can be harnessed to induce po...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338492/ https://ncbi.nlm.nih.gov/pubmed/30393066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.10.006 |
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