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In silico aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages

Cell specific delivery of therapeutic agents using ligand targeting is gaining interest due to the potential for increased efficacy and reduced side effects. The challenge is to develop a suitable ligand of a cell surface receptor that is selectively expressed on the desired cell. Sialoadhesin (Sn/S...

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Detalhes bibliográficos
Main Authors: Nycholat, Corwin M., Rademacher, Christoph, Kawasaki, Norihito, Paulson, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462166/
https://ncbi.nlm.nih.gov/pubmed/22967315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307501e
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