The Pat1-Lsm complex stabilizes ATG mRNA during nitrogen starvation-induced autophagy

Macroautophagy/autophagy is a key catabolic recycling pathway that requires fine-tuned regulation to prevent pathologies and preserve homeostasis. Here we report a new post-transcriptional pathway regulating autophagy involving the Pat1-Lsm (Lsm1 to Lsm7) mRNA-binding complex. Under nitrogen starvat...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Gatica, Damián, Hu, Guowu, Liu, Xu, Zhang, Nannan, Williamson, Peter R., Klionsky, Daniel J.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338489/
https://ncbi.nlm.nih.gov/pubmed/30527663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.002
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