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Randomized Phase II Trial of Cisplatin and Etoposide in Combination With Veliparib or Placebo for Extensive-Stage Small-Cell Lung Cancer: ECOG-ACRIN 2511 Study

PURPOSE: Veliparib, a poly (ADP ribose) polymerase inhibitor, potentiated standard chemotherapy against small-cell lung cancer (SCLC) in preclinical studies. We evaluated the combination of veliparib with cisplatin and etoposide (CE; CE+V) doublet in untreated, extensive-stage SCLC (ES-SCLC). MATERI...

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Bibliografiske detaljer
Udgivet i:J Clin Oncol
Main Authors: Owonikoko, Taofeek K., Dahlberg, Suzanne E., Sica, Gabriel L., Wagner, Lynne I., Wade, James L., Srkalovic, Gordan, Lash, Bradley W., Leach, Joseph W., Leal, Ticiana B., Aggarwal, Charu, Ramalingam, Suresh S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338394/
https://ncbi.nlm.nih.gov/pubmed/30523756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.00264
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