E5501 - Phase II Study of Topotecan Sequenced with Etoposide/Cisplatin, and Irinotecan/Cisplatin Sequenced with Etoposide for Extensive Stage Small Cell Lung Cancer

PURPOSE: Sequence dependent improved efficacy of topoisomerase I followed by topoisomerase 2 inhibitors was assessed in a randomized phase II study in extensive-stage small cell lung cancer (SCLC). METHODS: Patients with previously untreated extensive stage SCLC with measurable disease, ECOG perform...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Owonikoko, Taofeek K., Aisner, Joseph, Wang, Xin Victoria, Dahlberg, Suzanne E., Rubin, Eric H., Ramalingam, Suresh S., Gounder, Murugesan, Rausch, Paul Gregory, Axelrod, Rita S., Schiller, Joan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705842/
https://ncbi.nlm.nih.gov/pubmed/24288121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2338-z
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