Metformin Results in Diametrically Opposed Effects by Targeting Non-Stem Cancer Cells but Protecting Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma

Cancer stem cells (CSCs) have been shown as a distinct population of cancer cells strongly implicated with resistance to conventional chemotherapy. Metformin, the most widely prescribed drug for diabetes, was reported to target cancer stem cells in various cancers. In this study, we sought to determ...

Full description

Saved in:
Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kuo, Selena Z., Honda, Christine O., Li, Wei Tse, Honda, Thomas K., Kim, Elizabeth, Altuna, Xabier, Abhold, Eric, Wang-Rodriguez, Jessica, Ongkeko, Weg M.
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337486/
https://ncbi.nlm.nih.gov/pubmed/30621095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010193
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items