EGFR Kinase Promotes Acquisition of Stem Cell-Like Properties: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma Stem Cells

Members of the EGFR/ErbB family of tyrosine kinases are found to be highly expressed and deregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC). The ErbB family, including EGFR, has been demonstrated to play key roles in metastasis, tumorigenesis, cell proliferation, an...

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Detalhes bibliográficos
Main Authors: Abhold, Eric L., Kiang, Alan, Rahimy, Elham, Kuo, Selena Z., Wang-Rodriguez, Jessica, Lopez, Jay Patrick, Blair, Katherine J., Yu, Michael Andrew, Haas, Martin, Brumund, Kevin T., Altuna, Xabier, Patel, Andrew, Weisman, Robert A., Ongkeko, Weg M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288103/
https://ncbi.nlm.nih.gov/pubmed/22384257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032459
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