EGFR Kinase Promotes Acquisition of Stem Cell-Like Properties: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma Stem Cells

Members of the EGFR/ErbB family of tyrosine kinases are found to be highly expressed and deregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC). The ErbB family, including EGFR, has been demonstrated to play key roles in metastasis, tumorigenesis, cell proliferation, an...

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Autores principales: Abhold, Eric L., Kiang, Alan, Rahimy, Elham, Kuo, Selena Z., Wang-Rodriguez, Jessica, Lopez, Jay Patrick, Blair, Katherine J., Yu, Michael Andrew, Haas, Martin, Brumund, Kevin T., Altuna, Xabier, Patel, Andrew, Weisman, Robert A., Ongkeko, Weg M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288103/
https://ncbi.nlm.nih.gov/pubmed/22384257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032459
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